A partir de una encuesta por correo electrónico a estudiantes de Ingeniería en el SAI de la UAMA en un contexto de enseñanza remota forzado por la pandemia, se caracteriza la gestión de la docencia, desde la visión de los estudiantes, se realiza un diagnóstico de los aspectos relacionados. Es un estudio transversal con un análisis cualitativo y descriptivo de las respuestas. La gestión docente se ve afectada por factores inherentes al proceso, así como también por factores externos. Los resultados (...) obtenidos muestran que fue impactada fuertemente al realizarse el proceso totalmente vía remota especialmente, la comunicación e interacción alumno-profesor. (shrink)

Palabras claves. Métodos estadísticos, pruebas de hipótesisResumen. Se presentan de forma simple, breve y por medios de los ejemplos prácticos, los métodos estadísticos que sirven para demostrar la representatividad de una, dos o varias muestras basada en los parámetros poblacionales . Se indican la manera de reducir el tamaño del error experimental para aclarar el efecto significativo de los grupos o muestras bajo el interés . Además, se demuestran la forma de eliminar el efecto de las variables auxiliares o colaterales (...) causante del ruido o error en la estadística . También se nota el uso del modelo ANOVA Anidada para indicar la forma de segmentar la ANOVA en varias partes y de esta manera poder contestar preguntas más complejas. Finalmente, se describen e explican la forma de optimizar los recursos en la conducción de los experimentos y descubrir el efecto de la interacción entre las variables .Keywords. Hypothesis testing, statistical methods. Statistical methods that serve to represent, based upon population parameters of mean and variance, for one, tow or various samples taken from study populations are discussed. Ways to reduce the amount of experimental error in order to clarify the real effect of the treatments are demonstrated . The use of Covariance Analysis to show the pure effect of treatment free from the effect of collateral variables is also indicated. Nested ANOVA that allows division of ANOVA in several parts in order to answer complex questions is described and explained. Finally, the utility of Factorial Analysis for optimization of resource use as well as the illustration of interaction effects are noted and analyzed. (shrink)

Polyglutamine (polyQ) diseases are genetically inherited neurodegenerative disorders. They are caused by mutations that result in polyQ expansions of particular proteins. Mutant proteins form intranuclear aggregates, induce cytotoxicity and cause neuronal cell death. Protein interaction data suggest that polyQ regions modulate interactions between coiled‐coil (CC) domains. In the case of the polyQ disease spinocerebellar ataxia type‐1 (SCA1), interacting proteins with CC domains further enhance aggregation and toxicity of mutant ataxin‐1 (ATXN1). Here, we suggest that CC partners interacting with the polyQ (...) region of a mutant protein, increase its aggregation while partners that interact with a different region reduce the formation of aggregates. Computational analysis of genetic screens revealed that CC‐rich proteins are highly enriched among genes that enhance pathogenicity of polyQ proteins, supporting our hypothesis. We therefore suggest that blocking interactions between mutant polyQ proteins and their CC partners might constitute a promising preventive strategy against neurodegeneration. (shrink)

Reumen. Se describen las bases del muestreo conglomerado y muestreo sistemático. Se presentan lasecuaciones pertinentes y aquellas para la estimación del tamaño óptimo de muestreo para cada tipo demuestreo. Se demuestra la aplicación práctica de éstos clases de muestreo por medio de ejemplosreales.Palabras claves. Muestreo conglomerado, muestreo sistemático, tamaño óptimo de la muestra.. Cluster sampling and systematic sampling are described and their equations are provided.Real examples are given in order to show the applications of these types of samplings. Equations toestimate (...) optimal sample sizes are also noted.Keywords. Cluster sampling, optimal sample size, systematic sampling. (shrink)

The movement of Artificial Intelligence (AI) research from universities to big corporations has had a significant impact on the development of the field. In the past, AI research was primarily conducted in academic institutions, which foster a culture of peer reviewing and collaboration to enhance quality improvements. The growing interest in AI among corporations, especially regarding Machine Learning (ML) technology, has shifted the focus of research from quality to quantity. Corporations have the resources to invest in large-scale ML projects and (...) they are often more interested in fast results than in ensuring that AI algorithms are reliable and safe. This paper proposes that the description of a Darwinian process made by the mathematician and physicist Freeman Dyson can be used to understand the implications of ML research scenario. The context of the Darwinian process—or lack thereof—can be used to draw a parallel between historical and current implications of technology expansion strongly driven by economic interests, making clear the consequences of shifting AI research from academia to industry. Finally, this paper indicates future directions for AI research to create a healthier environment for the evolution of ML technology. (shrink)

El paradigma hermenéutico ha abierto un horizonte amplio a la hora de interpretar y comprender textos, pero ha cerrado las posibilidades existenciales que ya en Ser y tiempo abriera Heidegger. Lo que se intenta aquí es señalar esos presupuestos ontológico-existenciales que indicara acertadamente el filósofo alemán en su momento. El avance que se presenta hace parte del proyecto de investigación “Ontología en América Latina” que lidera el Grupo de Investigación Tlamatinime. La primera parte tiene como objetivo fijar cuatro lineamientos que (...) estructuran la propuesta de una hermenéutica existencial: 1. La disposición afectiva como afectación y responsabilidad. 2. El comprender afectivo. 3. El comprender como interpretación. 4. El sentido. La segunda parte, consiste en presentar lo que se vislumbra por hermenéutica existencial y cuál sería su propósito. (shrink)

This book reprints a wide variety of articles and speeches for the first time since they appeared in Spanish and foreign journals and in clandestine broadsheets from France. Some censored material has been restored.

Brain activity in the action observation network is lateralized during action execution, with greater activation in the contralateral hemisphere to the side of the body used to perform the task. However, it is unknown whether the AON is also lateralized when watching another person perform an action. In this study, we use fNIRS to measure brain activity over the left and right cortex while participants completed actions with their left and right hands and watched an actor complete action with their (...) left and right hands. We show that while activation is lateralized when the participants themselves are moving, brain lateralization is not affected by the side of the body when the participant is observing another person’s action. In addition, we demonstrate that individual differences in hand preference and dexterity between the right and left hands are related to brain lateralization patterns. (shrink)

In this paper we address the problem of short-term electric energy prediction using a time series forecasting approach applied to data generated by a Paraguayan electricity distribution provider. The dataset used in this work contains data collected over a three-year period. This is the first time that these data have been used; therefore, a preprocessing phase of the data was also performed. In particular, we propose a comparative study of various machine learning and statistical strategies with the objective of predicting (...) the electric energy consumption for a given prediction horizon, in our case seven days, using historical data. In this paper we have tested the effectiveness of the techniques with different historical window sizes. Specifically, we considered two ensemble strategies, a neural network, a deep learning technique and linear regression. Moreover, in this study, we tested whether the inclusion of meteorological data can help achieve better predictions. In particular, we considered data regarding temperature, humidity, wind speed and atmospheric pressure registered during the three-year period of data collection. The results show that, in general, the deep learning approach obtains the best results and that such results are obtained when meteorological data are also considered. Moreover, when meteorological data is used, a smaller historical window size is required to obtain precise predictions. (shrink)

En A Letter Concerning Toleration John Locke argumenta en favor de la tolerancia religiosa afirmando que el Estado no puede mejorar la vida de las personas forzándolas a vivir de acuerdo con creencias que ellas no suscriben. Más recientemente, Ronald Dworkin y Will Kymlicka han desarrollado argumentos similares. En el caso del primero, contra ciertas políticas paternalistas; en el del segundo, en apoyo de la tesis liberal de la neutralidad estatal. Mi propósito en el presente artículo es analizar la plausibilidad (...) de dichos argumentos concebidos como una defensa de la tesis de la neutralidad estatal. Intentaré demostrar que ambas versiones del argumento fracasan. En la sección II, cuestionaré la capacidad de los argumentos para respaldar las conclusiones que aspiran establecer, sin objetar la plausibilidad de las premisas involucradas. En la sección III, desarrollaré tres objeciones contra la concepción del bienestar crítico que constituye el corazón de ambas versiones del argumento. In A Letter Concerning Toleration, John Locke argues in favor of religious toleration positing that the state cannot make a person's life better by forcing that person to live according to beliefs he refuses. More recently, Ronald Dworkin and Will Kymlicka have developed similar arguments. In the first case, against some paternalistic policies; in the second, in support of the liberal ideal of state neutrality. My aim in the present paper is to analyze the plausibility of these arguments conceived as a defense of liberal neutrality. I will prove that both versions of the argument fail. In section II, I will object the argument's capability to support the conclusions it attempts to establish, without raising doubts about the reliability of its premises. In section III, I will submit three objections against the conception of critical well-being that constitutes the core of both versions of the argument. (shrink)

Miguel Díaz has succeeded quite well not only in providing support for popular Hispanic religion through an analysis of ideas from Karl Rahner, but skillfully meets several possible objections or alternatives. Nonetheless, the more sophisticated forms of Hispanic theology must also be sustained, if only to address adequately the transcendental atheism that the current and subsequent generation of Latino/a college students will encounter.

Miguel Díaz has succeeded quite well not only in providing support for popular Hispanic religion through an analysis of ideas from Karl Rahner, but skillfully meets several possible objections or alternatives. Nonetheless, the more sophisticated forms of Hispanic theology must also be sustained, if only to address adequately the transcendental atheism that the current and subsequent generation of Latino/a college students will encounter.

Authoritative and comprehensive interpretation of the Scottish philosopher's writings on religion.

The agonistic vs. epistemic dichotomy is fairly widespread in contemporary democratic theory and is endorsed by scholars as outstanding as Luis Felipe Miguel, Chantal Mouffe, and Nadia Urbinati. According to them, the idea that democratic deliberation can work as a rational exchange of arguments that aims at truth is incompatible with the recognition of conflict as a central feature of politics. In other words, the epistemic approach is bound to obliterate the agonistic and conflictive dimension of democracy. This article (...) takes this dichotomized way of thinking to task by reconstructing the association between democracy and compromise made by John Stuart Mill, John Morley, and Hans Kelsen. It concludes that the conceptualization of democracy as compromise offers an alternative to the agonistic vs. epistemic divide that disconcerts a significant part of political philosophy today. (shrink)

Caracterización de un grupo de comités de ética en investigación en Colombia Caracterização de um grupo de comitês de ética em pesquisa na Colômbia In the last decades, controlled clinical trials sponsored by the pharmaceutical industry have increased considerably. This has led to the need for greater control and assistance by regulators and ethics committees to ensure appropriate compliance with established ethical standards and good clinical practices in general. In Colombia, the National Food and Drug Surveillance Institute, the regulator in (...) the country, controls and monitors the operation of clinical research with drugs. In 2008, this entity issued Resolution 2378, which provides and regulates research actors in Colombia, including ethics committees. After being in force for several years, it is necessary to know whether research ethics committees in Colombia operate in accordance with this regulation and to determine the status of implementation of the requirements therein. For this purpose, a survey was designed to be voluntarily answered and a response was obtained from 25 of the 69 certified committees in Colombia. Twenty-two of them could be analyzed because their information was complete. Compared with previous studies, favorable changes in development and organization were observed in accordance with the current proposed regulation. Para citar este artículo / To reference this article / Para citar este artigo Suárez-Obando F, Reynales H, Urina M, Camacho J, Viteri M. Caracterización de un grupo de comités de ética en investigación en Colombia. pers. bioét. 2018; 22: 303-318. DOI: 10.5294/pebi.2018.22.2.8. (shrink)

The coexistence of genetically modified (GM) crops and non-GM crops is a myth because the movement of transgenes beyond their intended destinations is a certainty, and this leads to genetic contamination of organic farms and other systems. It is unlikely that transgenes can be retracted once they have escaped, thus the damage to the purity of non-GM seeds is permanent. The dominant GM crops have the potential to reduce biodiversity further by increasing agricultural intensification. There are also potential risks to (...) biodiversity arising from gene flow and toxicity to nontarget organisms from herbicide-resistant (HT) and insect-resistant (Bt) crops. Unless whole regions are declared GM agriculture free, the development of distinct systems of agriculture (GM and non-GM) will be impossible as GM agriculture emerges at the expense of all other forms of production. (shrink)